When denoising high ISO pictures, I found that doing the following is sometimes quite efficient:
Use the bilateral denoise with radius set to the maximum, red and blue to the maximum (or close) and green to the minimum.
The red and blue channels are frequently more noisy than the green one, and using this parameters allow to smooth them without losing too much details.
Please note that this technique is inefficient if any denoising smooths the color before this module in the pipeline. For example, if you use denoise profile with wavelet in “color” mode, this technique will not give proper result.
Thus, when I use it, I smooth color noise later in the pipeline, with a second bilateral denoise module in “color” mode
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