Insights or advise about: AMD Ryzen 5/7 CPU's and NVIDIA GTX/RTX GPU's

If you don’t also upgrade your heat transduction system overclocking will shorten MTBF, the mean time between failures. Overclocking also pushes the signal phase stability envelope toward physical limitations, your cpu, ram, and therefor computation all become more sensitive to ESD. If you can mitigate those limitations overclocking to 80% of the maximum frequency gain differential is ok based on a round-number headroom value. Your maximum will be determined by the transistor junction temperature in the cpu. The temperature is probed on the reverse side and thru the package. The BIOS and OS use the info to set fan voltage or pulse width. My cpu and heat sink will go up to 5.0GHz under full load before the chip thermal limiter cuts off power. It is rated for 3.9GHz maximum turbo frequency. That’s a difference of 1.1GHz. 80% of 1.1 is .88 so it runs normally at 3.9 + .88 = 4.78GHz. Going much past 5 would be pushing the frequency and phase-stability limitation of the motherboard, unless you’ve got some new hyper-spec 20G-integrity board.
I think many BIOS utilities will sense all this automatically after a number of reboots if you have a clock-unlocked processor.

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Thanks for that piece of information.

Seeing this mentioned is rather nice. The Ryzen 5 3600 is unlocked and the MSI B450M board is fully gen 3 ready. So this should work nicely.