I generally use DT for everything because it’s fast and the masks are easy to use for both landscapes and portraits, in my opinion. The profiled denoise just works, compared to RT where I still can’t get the hang of the luminance curve.
One thing that bothers me in DT is the lack of DCP support. You can convert the DCP into ICC and load it into DT, but I much prefer a simpler native solution. The effects of no DCP correction are shown in this post.