There's certainly nothing wrong with applying pre and post sharpening.
Many people follow the three stage sharpening philosophy https://www.cambridgeincolour.com/tutorials/image-sharpening.htm
The key here is that the first pass is to compensate for softness caused by the kit, e.g. AA filter, soft lens etc. It is important to keep this stage gentle and do not introduce artefacts like halos.
I use deconvolution for pre sharpening (warning this doesn't work well for noisy images)
and then unsharp mask with default settings for post resize sharpening (stage 3).
RT only has two sharpening stages, but any of the contrast tools (CBDL, edges, micro contrast, wavelet tools etc) can also be considered sharpening, because they increase apparent sharpness, and I would consider these as stage 2 creative sharpening.
As an aside @agriggio how easy would it be to allow for deconvolution and unsharp mask in the main tools, rather than having to select one or the other? I ask you because a) you've participated in this thread and b) I notice you're super keen and active in development (many thanks btw)